At a glance

About Polynucleotides

In recent years, the field of medical aesthetics has witnessed remarkable advancements, and one such breakthrough is the introduction of polynucleotide injectables. Natali Kelly Clinic stands at the forefront of this innovative treatment, offering patients a range of cutting-edge solutions for skin rejuvenation and anti-aging.

What are Polynucleotides?

Polynucleotide injectables, also known as PDRN (Polydeoxyribonucleotide), are a type of regenerative medicine that uses DNA fragments to stimulate tissue repair and regeneration. Derived from salmon DNA, these injectables contain nucleotides that mimic human DNA structure, making them highly compatible with our skin cells. When injected into the targeted areas, polynucleotide injectables promote collagen synthesis, enhance cell proliferation, and improve overall skin texture.


  • Skin Rejuvenation: Polynucleotide injectables stimulate the production of collagen and elastin, which are essential proteins for maintaining youthful and radiant skin. This leads to improved skin elasticity, reduced fine lines and wrinkles, and a more even skin tone.
  • Ameela Eyes is highly effective in reducing the visibility of eyebags and smoothing out wrinkles around the eyes.
  • Bio-restructuration of Deep Tissues.
  • Minimal Downtime: One of the advantages of polynucleotide injectables is that they require minimal downtime. Patients can resume their daily activities immediately after the treatment, making it a convenient option for busy individuals.
  • Ameela Eyes can be used as an adjunct to surgical procedures like blepharoplasty, lifting, and resurfacing laser treatments, aiding in recovery.


Many patients appreciate the convenience of Polynucleotides treatment due to its minimal downtime. You can typically resume your daily activities immediately after the treatment.


Is this treatment suitable for me?

All treatments require a consultation to assess if you are suitable. We do not treat those pregnant or breastfeeding.

What results can I expect?

We believe health and wellbeing should be balanced in order to achieve optimal beauty. Treatments are seen as ‘a journey to a new you’ and we support all clients with bespoke treatment plans to ensure you see the best results.

Are there any risks?

Our Medical Director Natali has hand-picked the most innovative procedures, technologies and high-performance team. Each Practitioner has their own approach with safety at their core and are aligned with our ethos. It is our goal to ensure all treatments performed protect your wellbeing. Risks versus benefits and your suitability, will be discussed in detail at your consultation.

What about aftercare?

Your aftercare will be discussed with your Practitioner during and following your treatment, you will also receive this by email. We are on hand to support your unique journey and welcome you to call or email us if you were to have any concerns. Including an out of hours emergency contact, for your complete reassurance.

What can I expect on the day?

From the moment you arrive our expert team strives to deliver excellence with a personal touch. Our beautiful clinic has been luxuriously designed to promote serenity and to encourage you to unwind and feel at home. All treatments are performed professionally and discretely, personalised for your individual journey. We welcome you to relax, meditate or pray in our Wellness lounge before and after your treatments.


We value feedback from our clients, here are some of our recent testimonials.

Natali Kelly - Patient FeedbackNatali Kelly - Patient Feedback

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